Wednesday, November 27, 2019

Bad Research Paper Example Essay Example

Bad Research Paper Example Paper A bad roommate in my opinion is someone who has little respect for personal space and belongings. They will consider cleanliness as any part of their style from the kitchen to the shared restroom, and everything in between its all Just one large mess! Also I have noticed bad roommates can become bothersome by the level of noise they create. Whether loud voices or bumping music from a set of speakers, It became a really big problem for me especially at 2 a. M. In the morning. With my first roommate I lived with that seemed like a problem that would never end! Another annoyance of a bad roommate is when he/she becomes unreliable. For example not having the money for the bills on the date they are due, or when the person fulfill their end of an agreement It becomes frustrating. Not only could It possibly affect your credit, but It also causes a stressful situation for the responsible roommate. Good roommate on the other hand has the qualities that you would consider a good friend to possess. It is better to find someone to room with that Is compatible with your needs. Bad Research Paper Example Essay Sample We will write a custom essay sample on Bad Research Paper Example specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on Bad Research Paper Example specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on Bad Research Paper Example specifically for you FOR ONLY $16.38 $13.9/page Hire Writer A Good or Bad Roommate A Good or Bad Roommate A Good or Bad Roommate Especially when it comes to cleanliness, animals, smoking, and even potential guests that may be coming through your house. A good roommate will always have respect for others wishes since it is not just their house alone. Good roommates also tend to give off a friendly vibe. You want to live with someone that is easy to communicate with so that there is no barrier between the two people. If you cannot communicate with your roommate then you might find out that your living in an unhealthy environment. Most importantly a good roommate has to be trustworthy.

Sunday, November 24, 2019

Dothiepin Vs. Fluoxetine (Mechanism Of Action And Essays

Dothiepin Vs. Fluoxetine (Mechanism Of Action And Essays Dothiepin Vs. Fluoxetine (Mechanism Of Action And Pharmacodynamics) Comparison Between Mechanism of Action and Pharmacodynamics of Dothiepin and Fluoxetine Description of medicines Mechanism of action and pharmacodynamics Dothiepin Dothiepin is a tricyclic antidepressant. It acts by promoting the effectiveness of several amines (dopamine, norepinephrine, and 5-hydroxytryptamine, which is also known as 5HT and serotonin). It functions by inhibiting their reuptake at the terminals of nerve cells, thus leading to their prolonged presence at the synaptic cleft and an increased effect on the neuron.(1) The reuptake pumps for the above amines are responsible for reducing the concentration of these amines. Dothiepin works by blocking the pumps. According to the amine hypothesis, a decreased concentration of the amines and the resulting decrease in amine dependant synaptic transmission is associated with depression, therefore an increase in the above would help relieve the symptoms of depression. (2) Dothiepin has other actions as well. It reduces norepinephrine induced CAMP formation in the brain, as well as inhibiting the uptake of 5HT into platelets. It also has some anticholinergic and antihistaminic activity.(3) Dothiepin begins to take effect after approximately 2-3 weeks. Usual daily doses of Dothiepin range from 75mg to 200mg in the more severe cases. (2) Fluoxetine Fluoxetine belongs to a group of antidepressants known as the SSRIs, or Selective serotonin reuptake inhibitors. It functions is similar to that of dothiepin above. It also acts as a reuptake inhibitor, but is highly selective. It only inhibits 5HT reuptake, and lacks many of the less useful functions of dothiepin, such as the antihistaminic properties. (1) As above the result in increase in the presence of serotonin at the synaptic cleft results in a decrease in many symptoms of depression. Fluoxetine does however have some side effects including nausea, tremors, loss of libido and in some cases decreased sexual function. (2) It is also possible that it may have an effect on dopamine function. In some cases it also reduces sleep efficiency. (3) Daily doses of Fluoxetine range between 10mg and 60mg. However it has been found that effectiveness does not appear to be strongly related to dose. 20mg is as affective as 40mg, and there is some evidence to suggest that higher doses may be even less effective. However the lower doses result in fewer and less sever adverse effects.(3) Adverse effects or adverse drug interactions Dothiepin Adverse effects of dothiepin range from potentially life threatening to mildly discomforting. Fatalities associated with dothiepin include cardiac failure, neonatal cardio-respiratory failure, myocardial infarction, arrhythmia, cardiac arrest, ventricular fibrillation, stroke, congenital heart disease, haematemesis, aplastic anemia, leukopenia, hepatorenal syndrome, cholestatic jaundice, coma, neuroleptic malignant syndrome, aggravated Parkinsons disease, intrauterine death, renal failure, respiratory arrest. These however are very rare. (1) Other severe side effects include hepatitis, inappropriate ADH secretion, hypomania, and convulsions. Psychotic manifestations, e.g. paranoid delusions, may be brought about or worsened if already present. These symptoms are also very uncommon, though less life threatening than those listed above.(3) The less dangerous side effects are a bit more common, found in many patients, particularly those on higher doses of the drug. These include dry mouth, tachycardia, constipation, drowsiness, sweating, nausea, vomiting, diarrhea, tremor, rashes, and interference with sexual function.(3) The greatest dangers in overdose stem from convulsions, and the cardiac and respiratory effects listed above. (3) Adverse drug interactions include MAO inhibitors and SSRI's as concurrent administration may lead to increased plasma tricyclic levels. CNS depressants, including alcohol will also have an increased effect when taken in conjunctions with dothiepin. Anesthetics may increase the risk of arrhythmia. Antihypertensive agent activity may be reduced by dothiepin. Barbiturates may decrease the serum concentration of dothiepin, while methyl phenidate may increase it. Smoking may reduce the serum concentration of dothiepin by increasing its metabolism. (1) Fluoxetine Fluoxetine appears to have a lower incidence of adverse reactions, and these appear less severe than those associated with dothiepin. (2) Up to 1990 a total of 11 deaths that may be associated with fluoxetine were recorded in patients. However these were not NECESSARILY associated with the drug. The potentially life threatening side effects included hyponatremia, which appeared to be reversible when the patients stopped taking the drug. A very few cases of vasculitis have also been diagnosed. Cases of seizures and seizure like episodes in fluoxetine patients have also been recorded. Some patients developed mania.

Thursday, November 21, 2019

Tax Havens or Offshore Financial Centre Thesis Example | Topics and Well Written Essays - 3500 words

Tax Havens or Offshore Financial Centre - Thesis Example Recently some countries have emerged as evident tax havens and are attracting hefty capital inflow. Singapore, Hong-Kong, Barbdos etc are only a few to name. "In Asia, offshore interbank markets began to develop after 1968 when Singapore launched the Asian Dollar Market (ADM) and introduced the Asian Currency Units (ACUs). The ADM was an alternative to the London euro-dollar market, and the ACU rule enabled mainly foreign banks to engage in international transactions under a favorable tax and regulatory environment"Similarly in Europe, Luxembourg attracted investors from Germany, France and Belgium in the early 1970s (IMF, 2000) due to its low income tax rates, the lack of withholding taxes for nonresidents on interest and dividend income, and banking secrecy rules. On the same ground The Channel Islands and the Isle of Man provided very similar opportunities. Moreover Bahrain began to serve as a collection center for the region's oil surpluses during the mid 1970s, after passing ban king laws and providing tax incentives to facilitate the incorporation of offshore banks. In the Western Hemisphere, the Bahamas and later the Cayman Islands provided similar facilities. Following this initial success by other countries, a number of other small countries tried to attract this business. Many had little success, because they were unable to offer any advantage over the more established centers. This did, however, lead some late arrivals to appeal to the less legitimate side of the business.